A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections.

@article{Noel2008ARD,
  title={A randomized, double-blind trial comparing ceftobiprole medocaril with vancomycin plus ceftazidime for the treatment of patients with complicated skin and skin-structure infections.},
  author={Gary J. Noel and Karen Bush and Partha Bagchi and Juliana Ianus and Richard S. Strauss},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2008},
  volume={46 5},
  pages={647-55}
}
BACKGROUND A randomized, double-blind, multicenter trial involving patients with a broad range of complicated skin and skin-structure infections due to either gram-positive or gram-negative bacteria was conducted to compare ceftobiprole monotherapy with treatment with vancomycin plus ceftazidime. METHODS Patients were randomized 2:1 to receive ceftobiprole or to receive vancomycin plus ceftazidime. Outcomes were determined at a test-of-cure visit (7-14 days after completion of therapy) and… CONTINUE READING
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Treatment of complicated skin and skin structure infections caused by grampositive bacteria with ceftobiprole: results of a double-blind, randomized trial

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2 Excerpts

In vivo anti-pseudomonal activity of ceftobiprole [abstract 198

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