A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomiting.

@article{Candiotti2008ARD,
  title={A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomiting.},
  author={Keith A Candiotti and Anthony L. Kovac and Timothy I Melson and Giuseppina Clerici and Tong Joo Gan},
  journal={Anesthesia and analgesia},
  year={2008},
  volume={107 2},
  pages={445-51}
}
BACKGROUND In this randomized, double-blind study we assessed the efficacy and safety of three different doses of the 5-HT(3) receptor antagonist palonosetron, compared with placebo, on the incidence and severity of postoperative nausea and vomiting (PONV) for 72 h postsurgery. METHODS Five hundred seventy-four patients undergoing either outpatient… CONTINUE READING