A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting.

@article{Gan2007ARD,
  title={A randomized, double-blind comparison of the NK1 antagonist, aprepitant, versus ondansetron for the prevention of postoperative nausea and vomiting.},
  author={Tong J Gan and Christian C. Apfel and Anthony L. Kovac and Beverly K. Philip and Neil Kumar Singla and Harold S. Minkowitz and Ashraf S Habib and Jennifer Knighton and Alexandra D. Carides and Hong Zhang and Kevin J Horgan and Judith K. Evans and Francasca C Lawson},
  journal={Anesthesia and analgesia},
  year={2007},
  volume={104 5},
  pages={1082-9, tables of contents}
}
BACKGROUND Antiemetics currently in use are not totally effective. Neurokinin-1 receptor antagonists are a new class of antiemetic that have shown promise for chemotherapy-induced nausea and vomiting. This is the first study evaluating the efficacy and tolerability of the neurokinin-1 receptor antagonist, aprepitant, for the prevention of postoperative… CONTINUE READING