A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting.

@article{Tariot2001ARD,
  title={A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting.},
  author={Pierre N. Tariot and Jeffrey L. Cummings and Ira R. Katz and Jacobo E. Mintzer and Carlos A. Perdomo and Elias M Schwam and E P Whalen},
  journal={Journal of the American Geriatrics Society},
  year={2001},
  volume={49 12},
  pages={1590-9}
}
OBJECTIVES To evaluate the safety and efficacy of donepezil in the management of patients with Alzheimer's disease (AD) residing in nursing home facilities. DESIGN Twenty-four-week, randomized, multicenter, parallel-group, double-blind, placebo-controlled trial. SETTING Twenty-seven nursing homes across the United States. PARTICIPANTS Two hundred eight nursing home patients with a diagnosis of probable or possible AD, or AD with cerebrovascular disease; mean Mini-Mental State Examination… CONTINUE READING