A randomized, double-blind, placebo-controlled tolerability study of intramuscular aripiprazole in acutely agitated patients with Alzheimer's, vascular, or mixed dementia.

@article{Rappaport2009ARD,
  title={A randomized, double-blind, placebo-controlled tolerability study of intramuscular aripiprazole in acutely agitated patients with Alzheimer's, vascular, or mixed dementia.},
  author={Stephen A Rappaport and Ronald N. Marcus and George Manos and Robert D. McQuade and Dan A. Oren},
  journal={Journal of the American Medical Directors Association},
  year={2009},
  volume={10 1},
  pages={21-7}
}
OBJECTIVES To evaluate the tolerability of intramuscular (IM) aripiprazole in patients with agitation associated with dementia. DESIGN A 24-hour, double-blind, placebo-controlled, randomized study. SETTING Sixteen healthcare facilities in the United States. PARTICIPANTS A total of 129 patients with acute agitation associated with Alzheimer's, vascular or mixed dementia in healthcare facilities. INTERVENTION Patients were randomized to IM aripiprazole (5 mg, 10 mg, or 15 mg) or IM… CONTINUE READING

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