A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis.

@article{Knobler2006ARD,
  title={A randomized, double-blind, placebo-controlled trial of photopheresis in systemic sclerosis.},
  author={Robert M. Knobler and Lars Einar French and Youn Kim and Emil Bisaccia and Winfried C. Graninger and Hesam Nahavandi and Frank J. Strobl and Edward C. Keystone and Marilyn A Mehlmauer and AlainH. Rook and Irwin M. Braverman},
  journal={Journal of the American Academy of Dermatology},
  year={2006},
  volume={54 5},
  pages={
          793-9
        }
}
BACKGROUND Systemic sclerosis is a multisystemic connective tissue disease with marked involvement of the skin and joints for which few effective evidence based therapies are available. To further investigate the efficacy of extracorporeal photochemotherapy on early aggressive cutaneous disease, a randomized, double-blind, placebo-controlled trial was performed. OBJECTIVE Our aim was to evaluate the efficacy of photopheresis in the treatment of patients with systemic sclerosis (scleroderma… CONTINUE READING
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