A randomized, double-blind, placebo-controlled study of maintenance treatment with adjunctive risperidone long-acting therapy in patients with bipolar I disorder who relapse frequently.

@article{Macfadden2009ARD,
  title={A randomized, double-blind, placebo-controlled study of maintenance treatment with adjunctive risperidone long-acting therapy in patients with bipolar I disorder who relapse frequently.},
  author={Wayne Macfadden and Larry D. Alphs and John Haskins and Norris G Turner and Ibrahim Turkoz and Cynthia A. Bossie and Mary J Kujawa and Ramy Mahmoud},
  journal={Bipolar disorders},
  year={2009},
  volume={11 8},
  pages={827-39}
}
OBJECTIVE No large controlled trials have evaluated adjunctive maintenance treatment with long-acting injectable antipsychotics in patients with bipolar disorder. This study assessed whether adjunctive maintenance treatment with risperidone long-acting therapy (RLAT), added to treatment-as-usual (TAU) medications for bipolar disorder, delays relapse in patients with bipolar disorder type I. METHODS This study included patients with bipolar disorder type I with > or = four mood episodes in the… CONTINUE READING

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