A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis.

@article{Elliott2004ARD,
  title={A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis.},
  author={Alison M Elliott and Henry Luzze and Maria A. Quigley and Jessica S Nakiyingi and Steven Kyaligonza and Proscovia Bazanya Namujju and Constance Ducar and Jerrold J. Ellner and James A G Whitworth and Roy D. Mugerwa and John Johnson and Alphonse Okwera},
  journal={The Journal of infectious diseases},
  year={2004},
  volume={190 5},
  pages={869-78}
}
BACKGROUND Active tuberculosis may accelerate progression of human immunodeficiency virus (HIV) infection by promoting viral replication in activated lymphocytes. Glucocorticoids are used in pleural tuberculosis to reduce inflammation-induced pathology, and their use also might reduce progression of HIV by suppressing immune activation. We examined the effect that prednisolone has on survival in HIV-1-associated pleural tuberculosis. METHODS We conducted a randomized, double-blind, placebo… CONTINUE READING

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