A randomized, double-blind, multicentre clinical trial comparing starting doses of 150 and 200 IU of recombinant FSH in women treated with the GnRH antagonist ganirelix for assisted reproduction.

@article{Out2004ARD,
  title={A randomized, double-blind, multicentre clinical trial comparing starting doses of 150 and 200 IU of recombinant FSH in women treated with the GnRH antagonist ganirelix for assisted reproduction.},
  author={Henk Jan Out and Anthony J. Rutherford and Richard Fleming and Clement C K Tay and Geoffrey H. Trew and William J. Ledger and David J. Cahill},
  journal={Human reproduction},
  year={2004},
  volume={19 1},
  pages={
          90-5
        }
}
BACKGROUND Studies with the GnRH antagonist ganirelix in assisted reproduction have indicated that compared with traditional GnRH agonist downregulation protocols, slightly fewer oocytes are retrieved. In this study it was investigated whether an increase in the starting dose of recombinant FSH (rFSH) could compensate for this loss. METHODS A randomized, double-blind, multicentre clinical trial comparing a starting dose of 150 and 200 IU of rFSH (follitropin beta), in women undergoing… 

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Agonist or antagonist: what is preferable for in vitro fertilization?
  • Z. Ben-Rafael
  • Biology, Medicine
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  • 2012
Control of ovarian stimulation with gonadotropin is a key factor in the success of IVF. Combining GnRH-analogs (agonists or antagonist) with stimulation protocols became the standard of care in all
...
...

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