A randomized, double-blind, crossover study of methylphenidate and lithium in adults with attention-deficit/hyperactivity disorder: preliminary findings.

@article{Dorrego2002ARD,
  title={A randomized, double-blind, crossover study of methylphenidate and lithium in adults with attention-deficit/hyperactivity disorder: preliminary findings.},
  author={Mar{\'i}a Flavia Dorrego and Lilia Canevaro and Gabriela Kuzis and Liliana Sabe and Sergio E. Starkstein},
  journal={The Journal of neuropsychiatry and clinical neurosciences},
  year={2002},
  volume={14 3},
  pages={289-95}
}
The authors examined the efficacy of methylphenidate (MPH) and lithium to treat attention-deficit/ hyperactivity disorder (ADHD) in adults, using a randomized, double-blind, crossover design. Patients received 8 weeks of MPH treatment (up to 40 mg/day) and 8 weeks of lithium treatment (up to 1,200 mg/day), by random assignment. Independent evaluators blind to group assignment assessed response every 2 weeks and at the end of each phase. The primary outcome measure was the Conners' Adult ADHD… CONTINUE READING