A randomized, double‐blind, placebo‐controlled trial of oral procyanidin with vitamins A, C, E for melasma among Filipino women

@article{Handog2009ARD,
  title={A randomized, double‐blind, placebo‐controlled trial of oral procyanidin with vitamins A, C, E for melasma among Filipino women},
  author={Evangeline B. Handog and Dulce Amor Vivan F Galang and Maria Azirrel de Leon-Godinez and G P Chan},
  journal={International Journal of Dermatology},
  year={2009},
  volume={48}
}
Background  Melasma is a common, acquired, symmetric hypermelanosis characterized by irregular brown to gray–brown macules on the cheeks, forehead, nasal bridge, cutaneous part of the upper lip, mandible, and the upper arms. Few trials have been conducted regarding the potential benefits of oral procyanidin in melasma. 
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