A randomized, controlled trial of omega-3 fatty acids plus an antioxidant for relapse prevention after antipsychotic discontinuation in first-episode schizophrenia.

@article{Emsley2014ARC,
  title={A randomized, controlled trial of omega-3 fatty acids plus an antioxidant for relapse prevention after antipsychotic discontinuation in first-episode schizophrenia.},
  author={Robin Emsley and Bonginkosi Chiliza and Laila Asmal and Stefan Simon du Plessis and Lebogang Phahladira and Evette Van Niekerk and Susan Janse van Rensburg and Brian Herbert Harvey},
  journal={Schizophrenia research},
  year={2014},
  volume={158 1-3},
  pages={230-5}
}
BACKGROUND While antipsychotics are effective in the maintenance treatment of schizophrenia they have safety and tolerability risks. We investigated whether a combination of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and a metabolic antioxidant, alpha-lipoic acid (α-LA), is effective in preventing relapse after antipsychotic discontinuation in subjects who were successfully treated for 2-3 years after a first-episode of schizophrenia, schizo-affective or schizophreniform disorder… CONTINUE READING
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ECDEU Assessment Manual for Psychopharmacology

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  • ADM 76–338US Department of Health, Education and…
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