A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury*

@article{Martin2005ARC,
  title={A randomized, controlled trial of furosemide with or without albumin in hypoproteinemic patients with acute lung injury*},
  author={Greg S. Martin and Marc Moss and Arthur P. Wheeler and Meredith Mealer and John A. Morris and Gordon R. Bernard},
  journal={Critical Care Medicine},
  year={2005},
  volume={33},
  pages={1681-1687}
}
Objective:Hypoproteinemia is a common condition in critically ill patients, associated with the development of acute lung injury and acute respiratory distress syndrome and subsequent worse clinical outcomes. Albumin with furosemide benefits lung physiology in hypoproteinemic patients with acute lung injury/acute respiratory distress syndrome, but the independent pharmacologic effects of these drugs are unknown. Design:Randomized, double-blinded, placebo-controlled multicentered trial. Setting… 
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TLDR
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Albumin and furosemide therapy improves fluid balance, oxygenation, and hemodynamics in hypoproteinemic patients with acute lung injury, with favorable trends in measures of intensive care.
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