A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women

@article{Murray2008ARS,
  title={A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women},
  author={Juliette Murray and Oliver E. Young and Lorna Renshaw and Sharon Andrews White and Linda D Williams and Dean B. Evans and Jeremy St. J. Thomas and Mitch Dowsett and J. M. Dixon},
  journal={Breast Cancer Research and Treatment},
  year={2008},
  volume={114},
  pages={495-501}
}
Introduction Changes in proliferation as measured by Ki67 occur within 14 days of starting treatment with an aromatase inhibitor and these changes have been shown to be predictors of long term outcome. This study aimed to compare changes in proliferation following 14 days of treatment with anastrozole and letrozole. Methods Two hundred and six women with 209 estrogen receptor (ER) positive operable breast cancers (three bilateral) were randomly allocated to receive either 14 days treatment with… CONTINUE READING
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1 Excerpt

Objective response to neoadjuvant letrozole predicts distant disease free survival in post-menopausal women with stage ii-iii ER/PgR positive breast cancer

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