A randomised study of 10 microg/kg/day (single dose) vs 2 x 5 microg/kg/day (split dose) G-CSF as stem cell mobilisation regimen in high-risk breast cancer patients.

@article{Carrin2003ARS,
  title={A randomised study of 10 microg/kg/day (single dose) vs 2 x 5 microg/kg/day (split dose) G-CSF as stem cell mobilisation regimen in high-risk breast cancer patients.},
  author={R. S{\'a}nchez Carri{\'o}n and David Serrano and Alfonso G{\'o}mez-Pineda and J. L. D{\'i}ez-Mart{\'i}n},
  journal={Bone marrow transplantation},
  year={2003},
  volume={32 6},
  pages={563-7}
}
A randomised trial in breast cancer patients was designed to compare the number of peripheral blood progenitor cells collected after mobilisation with a single dose of 10 microg/kg/day granulocyte colony-stimulating factor (G-CSF) (n=14) or a split dose of 5 microg/kg twice daily (n=14). Both groups were well balanced. No significant differences were observed between groups regarding aphereses parameters. The total number of CD34+ cells collected was higher in the split-dose group (mean of 7.1… CONTINUE READING

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