A randomised double‐blind study comparing the effect of 1072‐nm light against placebo for the treatment of herpes labialis

@article{Hargate2006ARD,
  title={A randomised double‐blind study comparing the effect of 1072‐nm light against placebo for the treatment of herpes labialis},
  author={G. Hargate},
  journal={Clinical and Experimental Dermatology},
  year={2006},
  volume={31}
}
  • G. Hargate
  • Published 2006
  • Medicine
  • Clinical and Experimental Dermatology
Background.  Previous research demonstrated that 1072‐nm narrowband laser light is effective in the treatment of cold sores. 
Evaluation of the efficacy of low‐level light therapy using 1072 nm infrared light for the treatment of herpes simplex labialis
  • G. Dougal, S. Y. Lee
  • Medicine
  • Clinical and experimental dermatology
  • 2013
TLDR
Low‐level light therapy (LLLT) using 1072 nm infrared light is effective in reducing the duration of herpes simplex labialis episodes and enhancing the healing process. Expand
Light‐emitting diodes in dermatology: A systematic review of randomized controlled trials
TLDR
The goal of this systematic review is to critically analyze published randomized controlled trials and provide evidence‐based recommendations on the therapeutic uses of LEDs in dermatology based on published efficacy and safety data. Expand
Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis
TLDR
Treatment with diode laser reduced the length of recovery time and pain severity faster than treatment with acyclovir cream and low level laser therapy. Expand
Efficacy of low-level laser therapy in management of recurrent herpes labialis: a systematic review
TLDR
It is suggested that laser is potentially a safe and effective treatment alternative for the management of RHL, however, due to high variability in study designs and inconsistency in laser parameters among the included studies, more well-designed randomized clinical trials with standardized laser parameters are highly warranted. Expand
Does low-level light therapy accelerate healing time of oral herpes simplex lesions?
TLDR
Direct application of low-level light therapy significantly accelerates the healing time of oral herpes simplex lesions and exhibited great patient satisfaction, as they did not have to endure unsightly facial lesions for a long duration of time, and their symptoms of pain and burning were significantly reduced. Expand
Phototherapy in the treatment of cutaneous herpesvirus manifestations.
TLDR
Evidence from the reviewed literature indicates that short-term efficacy from treatment with phototherapy is the most likely outcome, however, long-term effects and follow-up of this treatment modality are lacking but appear promising. Expand
Therapeutic Efficacy of Home-Use Photobiomodulation Devices: A Systematic Literature Review.
TLDR
Home-use PBM devices appear to mediate effective, safe treatments in a variety of conditions that require frequent applications, but conclusive evaluation of their efficacy requires additional, randomized controlled studies. Expand
Enhancement of cutaneous immune response to bacterial infection after low-level light therapy with 1072 nm infrared light: a preliminary study.
TLDR
1072 nm infrared light had a photobiomodulation effect which resulted in an enhanced biological immune response to the bacterial infection by MRSA and also increased the expression of VEGF to a significant level. Expand
Photobiomodulation and other light stimulation procedures.
The focus of this chapter is the visible and noninvisible near infrared electromagnetic frequency spectrum. We explore the biological and neurophysiological impact generated by visible and nearExpand
Current Status of Light-Emitting Diode Phototherapy in Dermatological Practice
Phototherapy in its broadest sense means any kind of treatment (from the Greek therapeia ‘curing, healing,’ from therapeuein ‘to cure, treat.’) with any kind of light (from the Greek phos, photosExpand
...
1
2
...

References

SHOWING 1-10 OF 25 REFERENCES
A pilot study of treatment of herpes labialis with 1072 nm narrow waveband light
TLDR
It is demonstrated that a single 5 min light treatment significantly reduced cold sore healing time by 4“days; 1072 nm light healed cold sores in 4.3 ± 1.8 days (mean ± SD) as compared with aciclovir applied five times daily, 8.5‰±‰3.0‰days (P < 0.0001). Expand
Acyclovir Cream for Treatment of Herpes Simplex Labialis: Results of Two Randomized, Double-Blind, Vehicle-Controlled, Multicenter Clinical Trials
TLDR
Acyclovir cream did not prevent the development of classical lesions (progression to vesicles, ulcers, and/or crusts) and there was a statistically significant reduction in the duration of lesion pain in both studies. Expand
Pathogenesis of herpes simplex labialis: experimental induction of lesions with UV light
  • S. Spruance
  • Medicine
  • Journal of clinical microbiology
  • 1985
To develop a model system of herpes simplex labialis which would enable the study of patients before lesion onset, five patients were exposed to various doses of UV light from a sunlamp at theirExpand
The natural history of ultraviolet radiation-induced herpes simplex labialis and response to therapy with peroral and topical formulations of acyclovir.
TLDR
ACV therapy can be efficacious, but some rapidly developing lesions are unresponsive to treatment, which suggests that more than one process may contribute to the pathogenesis of herpes labialis. Expand
Improvement of host response to sepsis by photobiomodulation
TLDR
Whether laser irradiation has a stimulatory effect on the immune response in sepsis using an animal model is determined and ATP‐MgCL2 appears to improve cellular energetics and decrease mortality. Expand
Topical treatment of cutaneous herpes simplex virus infections.
Topical antiviral chemotherapy has a number of potential advantages over systemic drug delivery for the treatment of cutaneous herpes simplex virus infections, including convenience; higher targetExpand
Cross-sectional study of recurrent herpes labialis. Prevalence and risk factors.
Consecutive blood donors at 25 sites in southern Wisconsin were interviewed in 1985 to ascertain recurrent herpes labialis histories, other perioral conditions, and status on possible predisposingExpand
Treatment modalities and medication recommended by health care professionals for treating recurrent herpes labialis.
TLDR
Variation in treatment modalities and recommendations by each health profession is found, despite the fact that patients reported similar triggers and concerns, according to individual patient need and health care professional's lack of knowledge. Expand
Effects of UV-B on the resistance against infectious diseases.
TLDR
It is concluded that UV-B radiation may affect the resistance against several non-skin-associated infectious diseases, which is probably caused by a defect in the specific lymphocyte response to the antigen. Expand
Laser modulation of human immune system: Inhibition of lymphocyte proliferation by a gallium‐arsenide laser at low energy
TLDR
The results indicate that laser irradiation at low energy can interfere with immune system in vitro, and similar modulation could potentially occur in human subjects exposed to laser irradiated in vivo. Expand
...
1
2
3
...