A radioimmunoassay that sandwiches human interleukin-2 between radiolabeled monoclonal antibody and the receptor on a hematopoietic cell line.

Abstract

Two monoclonal antibodies were raised against human interleukin-2 (IL-2) produced by E. coli harboring recombinant complemental DNA. Both antibodies did not neutralize its activity, nor did they inhibit the binding of IL-2 to the receptor on target cells. Taking advantage of the ability of monoclonal antibodies to detect IL-2 that had bound to the receptor… (More)

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Cite this paper

@article{Ohike1986ART, title={A radioimmunoassay that sandwiches human interleukin-2 between radiolabeled monoclonal antibody and the receptor on a hematopoietic cell line.}, author={Yumiko Ohike and M. Imai and E. Tanaka and Naoki Mukaida and T. Kasahara and K. Tachibana and Yoshitaka Miyakawa and Makoto Mayumi}, journal={Journal of immunological methods}, year={1986}, volume={87 2}, pages={245-9} }