A radioimmunoassay for the quantitative evaluation of anti-human acetylcholine receptor antibodies in myasthenia gravis.

@article{Monnier1977ARF,
  title={A radioimmunoassay for the quantitative evaluation of anti-human acetylcholine receptor antibodies in myasthenia gravis.},
  author={Vincent M. Monnier and Bernhard W. Fulpius},
  journal={Clinical and experimental immunology},
  year={1977},
  volume={29 1},
  pages={16-22}
}
A radioimmunoassay was developed for the quantitative evaluation of antibodies to the acetylcholine receptor in the serum of myasthenic patients. AcChR was extracted from human muscle. A detailed preparation of the 125I-labelled alpha-Bgt-AcChR complex used as antigen is reported. Usually, an average of 20 pmol were obtained form 100 g muscle. This… CONTINUE READING