A radiation-derived gene expression signature predicts clinical outcome for breast cancer patients.


Activation of the DNA damage response pathway is a hallmark for early tumorigenesis, while loss of pathway activity is associated with disease progression. Thus we hypothesized that a gene expression signature associated with the DNA damage response may serve as a prognostic signature for outcome in cancer patients. We identified ionizing radiation… (More)
DOI: 10.1667/RR1223.1


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