A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.

@article{Zhou2016ARM,
  title={A rabbit model of cerebral microembolic signals for translational research: preclinical validation for aspirin and clopidogrel.},
  author={Xiaoyan Zhou and Stan Kurowski and Weizhen Wu and Kunal Desai and Lin Chu and David E. Gutstein and Dietmar A. Seiffert and Xinkang Wang},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2016},
  volume={14 9},
  pages={1855-66}
}
UNLABELLED Essentials Microembolic signal (MES) is an independent predictor of stroke risk in patients. A rabbit model of cerebral microembolic signals was established. Therapeutic efficacy was demonstrated for aspirin and clopidogrel on microembolic signals. Potential translational value of this preclinical model of MES was demonstrated. SUMMARY Objectives Cerebral microembolic signals (MESs) detected by transcranial Doppler (TCD) ultrasound constitute an independent predictor of stroke risk… CONTINUE READING
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