A rabbit beta-globin polyadenylation signal directs efficient termination of transcription of polyomavirus DNA.


We constructed a viable insertion mutant (ins 5) of polyomavirus which contains, upstream of the L-strand polyadenylation signal, a 94-nt fragment of rabbit beta-globin DNA. Included in this fragment are all of the sequence elements required for efficient cleavage and polyadenylation of rabbit beta-globin RNA. The beta-globin signal was efficiently… (More)


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