A quarter of men with idiopathic oligo-azoospermia display chromosomal abnormalities and microdeletions of different types in interval 6 of Yq11

@article{Stuppia1998AQO,
  title={A quarter of men with idiopathic oligo-azoospermia display chromosomal abnormalities and microdeletions of different types in interval 6 of Yq11},
  author={Liborio Stuppia and Valentina Gatta and Giuseppe Calabrese and Paolo E. Guanciali Franchi and Elisena Morizio and Cristina Bombieri and Rita Mingarelli and Vincenzo Sforza and Giovanni Vanni Frajese and Raffaele Lanfranco Tenaglia and Giandomenico Palka},
  journal={Human Genetics},
  year={1998},
  volume={102},
  pages={566-570}
}
Cytogenetic investigations and molecular analysis of the Y chromosome by the polymerase chain reaction amplification of sequence-tagged sites (STS-PCR) technique were performed in 126 patients affected by idiopathic oligo-azoospermia following accurate selection of cases. Seventeen patients evidenced an abnormal karyotype. Fourteen patients with a normal karyotype had microdeletions of the Y chromosome within interval 6. In azo-ospermic patients microdeletions were scattered along different… CONTINUE READING