A quantitative study of spermatogonial multiplication and stem cell renewal in the C3H/101 F1 hybrid mouse.

@article{Tegelenbosch1993AQS,
  title={A quantitative study of spermatogonial multiplication and stem cell renewal in the C3H/101 F1 hybrid mouse.},
  author={R. A. J Tegelenbosch and Dirk G de Rooij},
  journal={Mutation research},
  year={1993},
  volume={290 2},
  pages={
          193-200
        }
}
In whole mounts of seminiferous tubules of C3H/101 F1 hybrid mice, spermatogonia were counted in various stages of the epithelial cycle. Furthermore, the total number of Sertoli cells per testis was estimated using the disector method. Subsequently, estimates were made of the total numbers of the different spermatogonial cell populations per testis. The results of the cell counts indicate that the undifferentiated spermatogonia are actively proliferating from stage XI until stage IV. Three… CONTINUE READING

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