A quantitative statistical analysis of the submentalis muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorder

@article{Ferri2008AQS,
  title={A quantitative statistical analysis of the submentalis muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorder},
  author={Raffaele Ferri and Mauro Manconi and Giuseppe Plazzi and Oliviero Bruni and Stefano Vandi and Pasquale Montagna and Luigi Ferini-Strambi and Marco Zucconi},
  journal={Journal of Sleep Research},
  year={2008},
  volume={17}
}
The aim of this study was to evaluate quantitatively the amplitude of the submentalis muscle EMG activity during sleep in controls and in patients with idiopathic REM sleep behavior disorder (RBD) or with RBD and multiple system atrophy (MSA). We recruited 21 patients with idiopathic RBD, 10 with MSA, 10 age‐matched and 24 young normal controls. The average amplitude of the rectified submentalis muscle EMG signal was used for the assessment of atonia and a Sleep Atonia Index was developed… 
Searching for a marker of REM sleep behavior disorder: submentalis muscle EMG amplitude analysis during sleep in patients with narcolepsy/cataplexy.
TLDR
This study shows that polysomnographically evident RBD is present in many patients with narcolepsy/ cataplexy, reflecting a peculiar form of REM sleep related motor dyscontrol, and correlated with the specific neurochemical and neuropathological substrate of narcoleonpsy.
Improved computation of the atonia index in normal controls and patients with REM sleep behavior disorder.
Night-to-night variability of automatic quantitative parameters of the chin EMG amplitude (Atonia Index) in REM sleep behavior disorder.
TLDR
The night-to-night variability of AI seems to be very low in normal controls and remains under 20% in RBD patients, however, even a single PSG recording provides high values of sensitivity and specificity when a threshold value of AI ≤ 0.9 is used to define abnormal chin EMG levels during REM sleep that increase only moderately when a second recording night is available.
Loss of rapid eye movement sleep atonia in patients with REM sleep behavioral disorder, narcolepsy, and isolated loss of REM atonia.
TLDR
Quantification of REM sleep EMG activity can successfully differentiate RBD and isolated loss of REM atonia patients from controls and indicates that this can be an additional marker for a diagnosis of narcolepsy.
Quantitative EMG criteria for diagnosing idiopathic REM sleep behavior disorder
TLDR
Identifying periods of tonic and phasic activities of the submentalis muscle during REM sleep is useful to discriminate patients with idiopathic RBD from controls.
A quantitative analysis of the submentalis muscle electromyographic amplitude during rapid eye movement sleep across the lifespan
TLDR
The results show that REM sleep atonia develops continuously during the lifespan, and undergoes complex changes with different developmental trajectories for REM atonia and electromyographic activations during REM sleep.
Modulation of the Muscle Activity During Sleep in Cervical Dystonia
TLDR
Patients with cervical dystonia reported poor sleep quality and showed impaired sleep architecture, which cannot be related to the persistence of muscle activity over the cervical muscles, which disappears in all the sleep stages, reaching significantly decreased values when compared to HC.
REM Sleep without atonia correlates with abnormal vestibular-evoked myogenic potentials in isolated REM sleep behavior disorder.
TLDR
Brainstem neurophysiology in iRBD can be assessed by VEMPs and their alterations may possibly indicate an early expression of the neurodegenerative process underlying this disorder at the brainstem level, which awaits future longitudinal confirmation.
...
...

References

SHOWING 1-10 OF 39 REFERENCES
Quantification of Electromyographic Activity During Sleep: A Phasic Electromyographic Metric
TLDR
Systematic application of a visual scoring system for short-duration phasic EMG activity recorded from five different muscle groups indicated that PEM is a normal part of REM sleep in all muscle groups and may be a useful metric amenable to quantification with digital techniques.
Validation of a polysomnographic score for REM sleep behavior disorder.
TLDR
This quantitative method to assess the severity of RBD polysomnographic features appears to be both valid and reliable in patients at risk for RBD because of neurodegenerative disorders.
Sleep disorders in multiple system atrophy: a correlative video-polysomnographic study.
A quantitative analysis of phasic and tonic submental EMG activity in human sleep
REM sleep behavior disorders in multiple system atrophy
TLDR
It is shown that RBD represents the most common clinical sleep manifestation and polysomnographic finding in patients with MSA and can frequently herald the appearance of other MSA symptoms by years.
Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD
TLDR
REM sleep behavior disorder-related symptoms and neurophysiologic features are qualitatively similar in RBD subjects with the idiopathic form, multiple system atrophy (MSA), and Parkinson disease (PD), suggesting a more severe dysfunction in the structures that modulate REM sleep.
Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome.
TLDR
Most narcoleptic patients show a high number of LMs that are significantly less periodic than those of patients with RLS, and PLM are in functional interrelationship with the cyclic alternating pattern, which is reduced in patients withNarcolepsy.
REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy.
TLDR
REM sleep without atonia and RBD were as frequent in Patients with progressive supranuclear palsy as in patients with Parkinson disease, suggesting that the downstream cause of parkinsonism, rather than its primary neuropathology (synucleinopathy vs tauopathy), is a key factor for REM sleep behavior disorder.
...
...