A quantitative map of protein sequence space for the cis‐defensin superfamily

@article{Shafee2019AQM,
  title={A quantitative map of protein sequence space for the cis‐defensin superfamily},
  author={Thomas M A Shafee and M. Anderson},
  journal={Bioinformatics},
  year={2019},
  volume={35},
  pages={743–752}
}
  • Thomas M A Shafee, M. Anderson
  • Published 2019
  • Biology, Computer Science, Medicine
  • Bioinformatics
  • Motivation: The cis‐defensins are a superfamily of small, cationic, cysteine‐rich proteins, sharing a common scaffold, but highly divergent sequences and varied functions from host‐defence to signalling. Superfamily members are most abundant in plants (with some genomes containing hundreds of members), but are also found across fungi and invertebrates. However, of the thousands of cis‐defensin sequences in databases, only have a handful have solved structures or assigned activities. Non… CONTINUE READING
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    References

    SHOWING 1-10 OF 68 REFERENCES
    Plant defensins: Common fold, multiple functions
    • 100
    The Defensins Consist of Two Independent, Convergent Protein Superfamilies.
    • 63
    • PDF
    Convergent evolution of defensin sequence, structure and function
    • 69
    Phylogenetic distribution, functional epitopes and evolution of the CSαβ superfamily
    • 97
    Phylogenetic distribution, functional epitopes and evolution of the CSalphabeta superfamily.
    • 37
    Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
    • 343
    Structure-Activity Relationships of Insect Defensins
    • 18
    • PDF