A quantitative map of protein sequence space for the cis‐defensin superfamily

@article{Shafee2019AQM,
  title={A quantitative map of protein sequence space for the cis‐defensin superfamily},
  author={Thomas M A Shafee and M. Anderson},
  journal={Bioinformatics},
  year={2019},
  volume={35},
  pages={743–752}
}
Motivation: The cis‐defensins are a superfamily of small, cationic, cysteine‐rich proteins, sharing a common scaffold, but highly divergent sequences and varied functions from host‐defence to signalling. Superfamily members are most abundant in plants (with some genomes containing hundreds of members), but are also found across fungi and invertebrates. However, of the thousands of cis‐defensin sequences in databases, only have a handful have solved structures or assigned activities. Non… Expand
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