A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice

@article{Wieczorek1994AQC,
  title={A quantitative comparison on the effects of benztropine, cocaine and nomifensine on electrically evoked dopamine overflow and rate of re-uptake in the caudate putamen and nucleus accumbens in the rat brain slice},
  author={W. Wieczorek and Z. Kruk},
  journal={Brain Research},
  year={1994},
  volume={657},
  pages={42-50}
}
  • W. Wieczorek, Z. Kruk
  • Published 1994
  • Biology, Medicine
  • Brain Research
  • Fast cyclic voltammetry has been used to study the relative importance of neuronal dopamine (DA) uptake and D2 autoreceptor stimulation on the control of the extracellular concentration of electrically evoked DA in rat brain slices containing aCPu and NAc. The degree of potentiation of DA overflow by benztropine, cocaine and nomifensine was always greater in the aCPu than in the NAc. Although EC50 values for the uptake blockers in the NAc were lower than in the aCPu, they were only… CONTINUE READING

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