A quantitative analysis software tool for mass spectrometry–based proteomics

@article{Park2008AQA,
  title={A quantitative analysis software tool for mass spectrometry–based proteomics},
  author={Sung Kyu Robin Park and John D. Venable and Tao Xu and John R. Yates},
  journal={Nature Methods},
  year={2008},
  volume={5},
  pages={319-322}
}
We describe Census, a quantitative software tool compatible with many labeling strategies as well as with label-free analyses, single-stage mass spectrometry (MS1) and tandem mass spectrometry (MS/MS) scans, and high- and low-resolution mass spectrometry data. Census uses robust algorithms to address poor-quality measurements and improve quantitative efficiency, and it can support several input file formats. We tested Census with stable-isotope labeling analyses as well as label-free analyses. 

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