A quantitative analysis of the expression of alpha-smooth muscle actin in mesangioproliferative (GnMes) glomerulonephritis.

Abstract

The aim of the study was to quantitatively assess the expression of alpha-SMA in the renal interstitium in GnMes cases. Two image analysis approaches (in grey scale and in spatial colour images) were used to determine correctly the presence of the reaction. In spatial evaluation, the mean area fraction of a-SMA in the renal interstitium was 3.63% +/- 1.29… (More)

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