A quality by design (QbD) study on enoxaparin sodium loaded polymeric microspheres for colon-specific delivery.

@article{Hales2017AQB,
  title={A quality by design (QbD) study on enoxaparin sodium loaded polymeric microspheres for colon-specific delivery.},
  author={Dana Hales and Laurian Vlase and Sebastian Alin Porav and Andreea Elena Bodoki and Lucian Barbu-Tudoran and Marcela Achim and Ioan Tomuţă},
  journal={European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences},
  year={2017},
  volume={100},
  pages={249-261}
}
The aim of this study was to apply quality by design (QbD) for pharmaceutical development of enoxaparin sodium microspheres for colon-specific delivery. The Process Parameters (CPPs) and Critical Quality Attributes (CQAs) were identified. A central composite experimental design was used in order to develop the design space of microspheres for colon-specific… CONTINUE READING