A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila.

@article{Prokopenko1999APE,
  title={A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila.},
  author={Sergei N. Prokopenko and Anthony M. Brumby and Louise O'Keefe and Louise Prior and Yawen He and Robert E. Saint and Hugo J. Bellen},
  journal={Genes & development},
  year={1999},
  volume={13 17},
  pages={2301-14}
}
Cytokinesis ensures the successful completion of the cell cycle and distribution of chromosomes, organelles, and cytoplasm between daughter cells. It is accomplished by formation and constriction of an actomyosin contractile ring that drives the progression of a cleavage furrow. Microinjection experiments and in vitro transfection assays have suggested a requirement for small GTPases of the Rho family in cytokinesis. Yet, the identity of proteins regulating Rho signaling pathways during… CONTINUE READING
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Cytokinesis

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  • Dynamics of cell division (ed. S.A. Endow and D.M…
  • 1998
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