A proton current associated with sour taste: distribution and functional properties.

@article{Bushman2015APC,
  title={A proton current associated with sour taste: distribution and functional properties.},
  author={Jeremy D Bushman and Wenlei Ye and Emily R Liman},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2015},
  volume={29 7},
  pages={3014-26}
}
Sour taste is detected by taste receptor cells that respond to acids through yet poorly understood mechanisms. The cells that detect sour express the protein PKD2L1, which is not the sour receptor but nonetheless serves as a useful marker for sour cells. By use of mice in which the PKD2L1 promoter drives expression of yellow fluorescent protein, we previously reported that sour taste cells from circumvallate papillae in the posterior tongue express a proton current. To establish a correlation… CONTINUE READING