A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins

@article{Corbett2007APS,
  title={A proteomic study of serum from children with autism showing differential expression of apolipoproteins and complement proteins},
  author={Blythe A Corbett and Aaron B. Kantor and Howard Schulman and Wynn L. Walker and Lisa Lit and Paul Ashwood and David M. Rocke and Frank R. Sharp},
  journal={Molecular Psychiatry},
  year={2007},
  volume={12},
  pages={292-306}
}
Modern methods that use systematic, quantitative and unbiased approaches are making it possible to discover proteins altered by a disease. To identify proteins that might be differentially expressed in autism, serum proteins from blood were subjected to trypsin digestion followed by liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) on time-of-flight (TOF) instruments to identify differentially expressed peptides. Children with autism 4–6 years of age (n=69) were… CONTINUE READING

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