A proteomic analysis of secretory proteins of a pre-vacuolar mutant of Candida albicans.

Abstract

S. cerevisiae mutants lacking VPS4 missort several vacuolar proteins to the extracellular space, including carboxypeptidase (CPY), vacuolar protease A (PrA), and vacuolar protease B (PrB). In addition, certain soluble secretory proteins, such as invertase and acid phosphatase, are missorted from the pre-vacuolar compartment (PVC) to the general secretory… (More)
DOI: 10.1016/j.jprot.2009.10.003

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