A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers.

@article{Schreiweis2007APA,
  title={A proteomic analysis of adult rat bone reveals the presence of cartilage/chondrocyte markers.},
  author={Melissa A Schreiweis and Jon P. Butler and Nalini H Kulkarni and Michael D. Knierman and Richard E. Higgs and David L. Halladay and Jude E. Onyia and John E. S. Hale},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={101 2},
  pages={466-76}
}
The non-mineral component of bone matrix consists of 90% collagenous, 10% non-collagenous proteins. These proteins regulate mineralization, growth, cell signaling and differentiation, and provide bone with its tensile strength. Expression of bone matrix proteins have historically been studied individually or in small numbers owing to limitations in analytical technologies. Current mass-spectrometric and separations technologies allow a global view of protein expression patterns in complex… CONTINUE READING

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