A proteomic analysis of C-reactive protein stimulated THP-1 monocytes

Abstract

C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentameric protein in plasma. Recently, a potential dissociation mechanism from the disc-shaped pentameric CRP (pCRP) into single monomers (monomeric or mCRP) has been described. It has been shown that mCRP has strong pro-inflammatory effects on monocytes. To further define… (More)
DOI: 10.1186/1477-5956-9-1

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@inproceedings{Eisenhardt2010APA, title={A proteomic analysis of C-reactive protein stimulated THP-1 monocytes}, author={Steffen U. Eisenhardt and Jonathon Habersberger and Karen T. Oliva and Graeme Iain Lancaster and Mustafa Ayhan and Kevin J. Woollard and Holger Bannasch and Gregory Rice and Karlheinz H. Peter}, booktitle={Proteome Science}, year={2010} }