A protein methylesterase involved in bacterial sensing.

  title={A protein methylesterase involved in bacterial sensing.},
  author={Jeffry B. Stock and Daniel E. Koshland},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={75 8},
A protein methylesterase has been identified in soluble extracts of Salmonella typhimurium and Escherichia coli. This enzyme catalyzes the hydrolysis of gamma-glutamyl methyl ester residues from membrane-bound 60,000-molecular weight proteins that are essential for chemotaxis. Analyses of methylesterase activity in a variety of chemotactically defective strains suggest that the methylesterase is a product of the cheX gene in Salmonella and the cheB gene in E. coli. In addition, the cheT gene… CONTINUE READING
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