A protein kinase from Xenopus eggs specific for ribosomal protein S6.

@article{Erikson1985APK,
  title={A protein kinase from Xenopus eggs specific for ribosomal protein S6.},
  author={Eleanor Erikson and James L. Maller},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 3},
  pages={742-6}
}
A protein kinase specific for ribosomal protein S6 has been purified from eggs of Xenopus laevis. As visualized on a silver-stained polyacrylamide gel, the major protein in the preparation migrated with a Mr of 90,000. Incubation of the enzyme preparation with [gamma-32P]ATP led to phosphorylation of this protein on serine residues. Upon glycerol gradient centrifugation, the S6 kinase activity and the Mr 90,000 protein both sedimented with a Mr of 50,000-55,000. Two-dimensional gel… CONTINUE READING
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