A protein interaction map for cell polarity development

  title={A protein interaction map for cell polarity development},
  author={Becky L. Drees and Bryan A Sundin and Elizabeth A Brazeau and Juliane P. Caviston and Guang-Chao Chen and Wei Guo and Keith G Kozminski and Michelle W. Lau and John J. Moskow and Amy Hin Yan Tong and Laura R. Schenkman and Amos McKenzie and Patrick Brennwald and Mark S. Longtine and Erfei Bi and Clarence S.M. Chan and Peter J. Novick and Charles Boone and John R. Pringle and Trisha N. Davis and Stanley Fields and David G Drubin},
  journal={The Journal of Cell Biology},
  pages={549 - 576}
Many genes required for cell polarity development in budding yeast have been identified and arranged into a functional hierarchy. Core elements of the hierarchy are widely conserved, underlying cell polarity development in diverse eukaryotes. To enumerate more fully the protein-protein interactions that mediate cell polarity development, and to uncover novel mechanisms that coordinate the numerous events involved, we carried out a large-scale two-hybrid experiment. 68 Gal4 DNA binding domain… CONTINUE READING
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