A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries.

Abstract

Although the vertebrate embryonic midline plays a critical role in determining the left/right asymmetric development of multiple organs, few genes expressed in the midline are known to function specifically in establishing laterality patterning. Here we show that a gene encoding protein disulfide isomerase P5 (PDI-P5) is expressed at high levels in the… (More)

Topics

9 Figures and Tables

Cite this paper

@article{Hoshijima2002APD, title={A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries.}, author={Kazuyuki Hoshijima and James E Metherall and David Jonah Grunwald}, journal={Genes & development}, year={2002}, volume={16 19}, pages={2518-29} }