A protein chip designed to differentiate visually antibodies in chickens which were infected by four different viruses.

@article{Wang2010APC,
  title={A protein chip designed to differentiate visually antibodies in chickens which were infected by four different viruses.},
  author={Xiurong Wang and Lin Shi and Qimeng Tao and Hongmei Bao and Jianan Wu and Dongdong Cai and Fumei Wang and Yuhui Zhao and Guobin Tian and Yanbing Li and Chuanling Qao and Hualan Chen},
  journal={Journal of virological methods},
  year={2010},
  volume={167 2},
  pages={119-24}
}
This study aimed to develop a visual protein chip that can differentiate the antibodies induced by avian influenza virus, Newcastle disease virus, infectious bronchitis virus and infectious bursal disease virus, simultaneously. Proteins from the four viruses were purified and spotted onto an aldehyde group-modified glass slide at 2mg/ml. After that, the protein chip was reacted with the corresponding positive serum against these viruses, hybridized with a colloidal gold-labeled secondary… CONTINUE READING