A prospective trial of risk factors for sulfonylurea-induced hypoglycemia in type 2 diabetes mellitus.


CONTEXT Retrospective studies have identified oral sulfonylureas, age, and fasting as major risk factors for hypoglycemia in patients with type 2 diabetes. Sulfonylureas may be withheld from elderly patients out of concern for hypoglycemia. OBJECTIVE To evaluate the hypoglycemic effects of maximum doses of once-daily second-generation sulfonylureas… (More)