A prospective surveillance study of factor VIII inhibitor development in the Canadian haemophilia A population following the switch to a recombinant factor VIII product formulated with sucrose.

@article{Rubinger2008APS,
  title={A prospective surveillance study of factor VIII inhibitor development in the Canadian haemophilia A population following the switch to a recombinant factor VIII product formulated with sucrose.},
  author={Morel Rubinger and David Lillicrap and G E Rivard and JeromeM. Teitel and Manuel D Carcao and Chris Hensman and I Rev. Lucius Walker},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2008},
  volume={14 2},
  pages={
          281-6
        }
}
The introduction of new factor concentrates has, at times, resulted in an increase in inhibitor development; hence large systematic surveys of inhibitor development are necessary whenever new products are introduced. This study presents the results of a surveillance study conducted by the Inhibitor Subcommittee of the Association of Hemophilia Clinic Directors of Canada that evaluated inhibitor development in patients with haemophilia A following the switch to a second generation recombinant… CONTINUE READING
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