A prospective study of telomere length and the risk of skin cancer.

@article{Han2009APS,
  title={A prospective study of telomere length and the risk of skin cancer.},
  author={Jiali Han and Abrar A. Qureshi and Jennifer Prescott and Qun Guo and L Ye and David J. Hunter and Immaculata De Vivo},
  journal={The Journal of investigative dermatology},
  year={2009},
  volume={129 2},
  pages={415-21}
}
Telomere length is important in tumorigenesis. Using quantitative real-time PCR, we prospectively measured relative telomere length in a nested case-control study within the Nurses' Health Study: 218 melanoma cases, 285 squamous-cell carcinoma (SCC) cases, 300 basal-cell carcinoma (BCC) cases, and 870 controls. We observed that shorter telomeres were associated with a decreased number of moles (P=0.002) and a decreased risk of melanoma. Women in the second and first quartiles, those with the… CONTINUE READING