A prospective study of plasma C-peptide and colorectal cancer risk in men.

@article{Ma2004APS,
  title={A prospective study of plasma C-peptide and colorectal cancer risk in men.},
  author={Jing Ma and Edward L. Giovannucci and Michael D Pollak and Azita Leavitt and Yuzhen Tao and J. Michael Gaziano and Meir Jonathan Stampfer},
  journal={Journal of the National Cancer Institute},
  year={2004},
  volume={96 7},
  pages={546-53}
}
BACKGROUND Colorectal cancer and type 2 diabetes share many risk factors, and hyperinsulinemia appears to be associated with an increased risk of colorectal cancer. We used the concentration of plasma C-peptide (an indicator of insulin production) to determine whether insulin and insulin resistance are associated with the risk of developing colorectal cancer. METHODS We conducted a nested case-control study in the Physicians' Health Study. Plasma samples were collected from 14 916 cancer-free… CONTINUE READING

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