A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsia.

@article{Qiu2004APS,
  title={A prospective study of maternal serum C-reactive protein concentrations and risk of preeclampsia.},
  author={Chungfang Qiu and David Luthy and Cuilin Zhang and Scott W. Walsh and Wendy M Leisenring and Michelle A. Williams},
  journal={American journal of hypertension},
  year={2004},
  volume={17 2},
  pages={154-60}
}
BACKGROUND We measured C-reactive protein (CRP), a clinical marker of systemic inflammation, in maternal serum collected at 13 weeks gestation on average, to determine whether elevations precede the clinical manifestation of preeclampsia. METHODS Using a prospective, nested, case-control study design we measured CRP concentrations using a competitive immunoassay in 60 women who developed preeclampsia and in 506 women who remained normotensive throughout pregnancy. Logistic regression… CONTINUE READING

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