A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.

@article{BarrettConnor1986APS,
  title={A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease.},
  author={Elizabeth Barrett-Connor and Kay Tee Khaw and Samuel Yen},
  journal={The New England journal of medicine},
  year={1986},
  volume={315 24},
  pages={1519-24}
}
It has been postulated that dehydroepiandrosterone (DHEA) and its sulfate ester, dehydroepiandrosterone sulfate (DHEAS), the major secretory products of the human adrenal gland, may be discriminators of life expectancy and aging. We examined the relation of base-line circulating DHEAS levels to subsequent 12-year mortality from any cause, from cardiovascular disease, and from ischemic heart disease in a population-based cohort of 242 men aged 50 to 79 years at the start of the study. Mean DHEAS… CONTINUE READING
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