A prospective study of cognitive function and onset of dementia in cognitively healthy elders.

@article{Rubin1998APS,
  title={A prospective study of cognitive function and onset of dementia in cognitively healthy elders.},
  author={Eugene H. Rubin and Martha Storandt and J. Philip Miller and D A Kinscherf and Elizabeth A. Grant and John C. Morris and Leonard Berg},
  journal={Archives of neurology},
  year={1998},
  volume={55 3},
  pages={395-401}
}
OBJECTIVE To examine the earliest cognitive changes associated with the onset of dementia as well as changes associated with normal aging. DESIGN Longitudinal evaluation of participants with annual clinical and psychometric examinations for up to 15 1/2 years. SETTING AND PARTICIPANTS Elderly volunteers (n = 82) enrolled with a Clinical Dementia Rating of 0 (cognitively intact) in longitudinal studies. INTERVENTIONS None. MAIN OUTCOME MEASURES Clinical Dementia Rating and results of a 1… CONTINUE READING

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