A prospective randomized controlled study of the effect of short coincubation of gametes during insemination on zona pellucida thickness.

@article{Dirnfeld2003APR,
  title={A prospective randomized controlled study of the effect of short coincubation of gametes during insemination on zona pellucida thickness.},
  author={Martha Dirnfeld and Hanna Shiloh and David Bider and Eyal Harari and Mara Koifman and S Lahav-Baratz and Haim Abramovici},
  journal={Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology},
  year={2003},
  volume={17 5},
  pages={397-403}
}
A prospective, randomized study was conducted to evaluate the thickness, of zona pellucida (ZP) after brief or standard exposure of human oocytes to spermatozoa, and to determine the correlation between ZP thickness, fertilization rate and embryo quality. The mean ZP thickness 48 h after insemination was found to be significantly less in fertilized oocytes than in non-fertilized oocytes in all treated groups (13.72 +/- 3.0 microns and 15.08 +/- 2.5 microns, respectively; p < 0.007). Zona… CONTINUE READING