A prospective case-control study to investigate retinal microvascular changes in acute dengue infection

  title={A prospective case-control study to investigate retinal microvascular changes in acute dengue infection},
  author={Petrina Tan and David Chien Boon Lye and Tun Kuan Yeo and Carol Yim-lui Cheung and Tun Linn Thein and Joshua Guo Xian Wong and Rupesh V Agrawal and Lingjun Li and Tien Yin Wong and Victor C. Gan and Yee Sin Leo and Stephen Teoh},
  journal={Scientific Reports},
Dengue infection can affect the microcirculation by direct viral infection or activation of inflammation. We aimed to determine whether measured retinal vascular parameters were associated with acute dengue infection. Patients with acute dengue were recruited from Communicable Diseases Center, Singapore and age-gender-ethnicity matched healthy controls were selected from a population-based study. Retinal photographs were taken on recruitment and convalescence. A spectrum of quantitative retinal… 
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