A prospective, randomized, placebo-controlled trial of prednisone and allopurinol in the prevention of ERCP-induced pancreatitis.

@article{Budzyska2001APR,
  title={A prospective, randomized, placebo-controlled trial of prednisone and allopurinol in the prevention of ERCP-induced pancreatitis.},
  author={Agnieszka Budzyńska and Tomasz A Marek and Andrzej Nowak and Roman Kaczor and Ewa Nowakowska-Dulawa},
  journal={Endoscopy},
  year={2001},
  volume={33 9},
  pages={766-72}
}
BACKGROUND AND STUDY AIMS Acute pancreatitis is the most frequent and difficult-to-avoid complication of endoscopic retrograde cholangiopancreatography (ERCP). Corticosteroids, potent anti-inflammatory drugs, and allopurinol--a xanthine oxidase inhibitor that blocks the generation of oxygen-derived free radicals--may be potentially effective in preventing post-ERCP pancreatitis. The aim of this prospective study was to determine the effect of prophylactic oral corticosteroids and allopurinol on… CONTINUE READING
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